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Table 2 Classification of heart failure by LVEF on examination

From: Diagnosis and treatment of heart failure with preserved ejection fraction in patients on hemodialysis

Phenotype

LVEF

Definition

Heart failure with reduced ejection fraction: HFrEF

 < 40%

Left ventricular systolic dysfunction. In many clinical studies, patients with a low LVEF despite standard medical treatment for heart failure are enrolled as patients with HFrEF

Heart failure with preserved ejection fraction: HFpEF

 ≥ 50%

Left ventricular diastolic dysfunction. Other diseases that may cause similar symptoms should be ruled out. No effective treatments have been established

Heart failure with mid-range ejection fraction: HFmrEF

40% to < 50%

Borderline heart failure. Clinical features and prognosis have not yet been fully characterized. Treatment should be selected on an individual basis

  1. LVEF left ventricular ejection fraction