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Table 3 Classification of heart failure based on time-dependent changes in LVEF

From: Diagnosis and treatment of heart failure with preserved ejection fraction in patients on hemodialysis

Changes in phenotype

Definition

Heart failure with recovered EF: HFrecEF

LVEF improved during the treatment course and the condition transitioned from HFrEF to HFmrEF or HFpEF, or from HFmrEF to HFpEF

The outcome is relatively favorable

Heart failure with worsened EF: HFworEF

LVEF decreased with the treatment course and the condition transitioned from HFpEF to HFmrEF or HFrEF, or from HFmrEF to HFrEF

The outcome is poor

Heart failure with unchanged EF: HFuncEF

No major change is observed in LVEF throughout the course

  1. HFmrEF heart failure with mid-range ejection fraction, HFpEF heart failure with preserved ejection fraction, HFrEF heart failure with reduced ejection fraction, LVEF left ventricular ejection fraction